CASE REPORT Massive Fatal Pulmonary Emboli with Fibrinolytic Therapy
نویسندگان
چکیده
IN 1-2% of patients with deep vein thrombosis (DVT), pulmonary emboli develop despite therapy with heparin.' Episodes of DVT successfully treated with anticoagulant therapy may still result in venous valvular incompetence and lead to postphlebitic syndromes characterized by ulceration, varicosities and edema. Studies of thrombolytic agents suggest that early use of these drugs for extensive venoocclusive disease may preserve venous valvular competence and produce more rapid resolution of pulmonary emboli.2' " However, the role for thrombolytic therapy is undefined in cases where extensive DVT composed of segments of varying ages exists. It has been assumed that the creation of a systemic fibrinolytic state would protect against the development of pulmonary emboli
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